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Continuing Medical Education (CME): The American Society of Cytopathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The American Society of Cytopathology designates this enduring educational activity for a maximum of 1 AMA PRA Category 1 credit(s).TM Physicians should only claim credit commensurate with the extent of their participation in the activity.
American Board of Pathology Maintenance of Certification (MOC): This product can help fulfill the CME requirements and Self-Assessment Modules (SAMs) mandated by the American Board of Pathology MOC process.
Continuing Medical Laboratory Education (CMLE): The ASC designates this activity for the indicated number of CMLE credit hours and also fulfills requirements of the ABMS to participate in the Maintenance of Certification program.
This program is approved for continuing education credits in the State of Florida for 1 credit and the State of California for ½ credit.
A 70 year old female had a history of well-differentiated neuroendocrine tumor (WDNET) of the stomach arising from autoimmune metaplastic atrophic gastritis (AMAG). The follow-up positron emission tomography (PET) showed a 2.3 cm right paratracheal lesion, level 4R (superior mediastinum). A EUS-FNA was performed. The images of conventional FNA smears are shown in Figure 1.
Overall, the conventional smears were hypercellular. The cells were arranged in cohesive or loosely cohesive clusters as well as flat sheets. The cells were small, uniform in size, round or oval in shape, and had smooth nuclear couture. Papanicolaou stain demonstrated fine chromatin with “salt and pepper” appearance. The background was clean with no necrosis or cellular fragments/ debris. Immunohistochemical (IHC) stains demonstrated positivity for cytokeratin AE1/3, synaptophysin, chromogranin, and GATA3.